The Viral Salmon Sperm Facial Everyone Is Talking About: Rejuran Microneedling at Sisu Clinic USA

If you have been on TikTok recently, you have probably seen it.

Someone sits in a clinic chair. A practitioner moves a microneedling device across their skin. The content creator winces slightly, then shows the camera a face that is pink, a little swollen, and unmistakably glowing within days. The caption says something like: "salmon sperm facial" or "the treatment Korean women have been doing for years."

That treatment is Rejuran. And it is no longer just a TikTok curiosity.

Rejuran searches have grown 213% year over year on Google, averaging 35,600 monthly searches in the US. TikTok views of the treatment hit 5.1 million per week in early 2026. It has been linked to Kim Kardashian and Jennifer Aniston. It is the treatment patients are now walking into Sisu Clinic asking about by name.

Dr. Katie Livingstone, an injector at Sisu Clinic Ireland, has been using Rejuran with microneedling for years. She has a clear view on the hype.

At Sisu Clinic USA, Rejuran microneedling is available from $700 per session, with packages of two sessions at $1,350 and three sessions plus a free skin booster at $2,000. A free consultation is included.

What is Rejuran and why is it going viral?

Rejuran is a Korean-developed skin treatment powered by PDRN, which stands for polydeoxyribonucleotide. PDRN is derived from purified salmon sperm, which is exactly where the viral name comes from. The ingredient has been used clinically in South Korea for decades and is a staple in Korean dermatology for skin repair, barrier restoration and collagen support.

At Sisu Clinic, Rejuran is delivered using a microneedling pen. The device creates tiny micro-channels in the skin, and the Rejuran formula is applied directly to those channels, allowing it to penetrate into the dermis where it can get to work at a cellular level.

"The reason we use microneedling to deliver Rejuran rather than applying it topically is depth," Dr. Katie explains. "The active ingredient needs to reach the dermis to stimulate the repair response. Microneedling gives it that pathway. Without it, you are essentially putting an expensive ingredient on the surface of the skin and hoping for the best."

What does Rejuran microneedling treat?

The treatment is particularly well suited to patients dealing with post-summer skin concerns, but its clinical applications are broader:
• Dull, dehydrated or tired-looking skin
• Uneven skin tone and post-summer pigmentation
• Fine lines and early wrinkles
• Acne scars and textured skin
• Enlarged pores
• Under-eye fatigue and crepiness
• Weakened skin barrier and redness

It is suitable for most skin types, including darker skin tones, and is one of the treatments Dr. Katie most commonly recommends for patients who want visible improvement in skin quality without changing their facial structure or adding volume.

Why now is the right time to start a course

Dr. Katie has a consistent observation about timing, and it applies just as much in the US as it does in Ireland.

Every September, patients arrive at her clinic in Ireland describing the same thing: skin that looks dull, uneven or more tired than it did in spring. Pigmentation has deepened. Fine lines feel more visible. The culprit, in most cases, is the cumulative UV exposure of the summer months.

What to expect at your Sisu Clinic appointment

The session itself takes around 30 to 45 minutes. A topical numbing cream is applied beforehand to keep the treatment comfortable. The medical injector then uses a microneedling pen to create micro-channels across the treatment area, before applying the Rejuran formula directly to the skin.

Most patients describe the sensation as a mild prickling or warmth. Immediately after treatment, the skin will appear pink and feel sensitive, similar to a mild sunburn. Small pinpoint marks from the microneedling are normal and fade within 24 to 48 hours.

Aftercare
• Avoid makeup and active skincare for 48 hours post-treatment
• Apply SPF daily and avoid direct sun exposure
• Avoid saunas, steam rooms and strenuous exercise for 48 hours
• Use gentle, fragrance-free products in the days following treatment
• Avoid fake tan for at least 7 days before and 14 days after treatment

Who is suitable?

Rejuran microneedling is appropriate for most skin types, including darker skin tones. It is particularly well suited to patients with sun-damaged skin, post-acne scarring, or skin that has lost resilience and radiance.

Patients who may not be suitable include those who are pregnant, have active skin infections in the treatment area, or have certain medical conditions. A full consultation and medical history review is conducted before any treatment at Sisu Clinic.

Ready to book? Consult with the Sisu Clinic medical team at your nearest location in New York City, Houston or Florida. The consultation is free, there is no obligation and the treatment plan will be built around your skin.