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The Best Botox and Filler Treatments on the Upper East Side NYC

The Best Botox and Filler Treatments on the Upper East Side NYC
27 March 2026
What's New at Sisu

If you live or work on the Upper East Side and you've been thinking about aesthetic treatments — Botox, fillers, TrapTox, Sculptra — you already know that not all clinics are equal. The neighbourhood has options, but finding a clinic that combines medical credibility with natural results and transparent pricing takes a bit more than a quick Google search.

That's exactly why Sisu Clinic opened on Lexington Avenue. This is our third New York City location — joining SoHo and Flatiron — and it brings the same doctor-led standard that's earned Sisu thousands of five-star reviews globally to one of Manhattan's most discerning neighbourhoods.

Here's a breakdown of the treatments available at Sisu Clinic Upper East Side and what makes each one worth knowing about.

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Botox™ and Dysport™ on the Upper East Side

Botox and Dysport remain the most requested aesthetic treatments in New York City — and for good reason. When done well, they smooth expression lines, refresh the face, and leave you looking like yourself, just rested.

At Sisu Clinic Upper East Side, Botox™ and Dysport™ are used to treat forehead lines, frown lines, crow's feet, and a wide range of other areas including brow lifting, gummy smile correction, lip flip, masseter slimming, and hyperhidrosis (excessive sweating).

Every treatment is delivered by Emily Canavarros, BSN, RN — a medically trained aesthetic injector with advanced clinical training and a particular focus on natural, balanced results.

What sets Sisu apart for Botox on the Upper East Side is the doctor-founded framework behind every treatment. Sisu was built by doctors, and the clinical protocols used across all 27 locations worldwide apply here too — conservative technique, anatomical precision, and a genuine focus on what your face needs rather than what sells.

If you're searching for Botox on the Upper East Side and want results that don't shout, Sisu is worth a consultation.

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Lip Filler on the Upper East Side

Lip filler has come a long way. The over-filled, duck-lip aesthetic that made people hesitant a decade ago is not what good lip filler looks like today — and Sisu's approach makes that very clear.

At our Upper East Side clinic, lip filler treatments use premium hyaluronic acid to add shape, definition and subtle volume in proportion with the rest of your face. Whether you want a barely perceptible enhancement to restore lip volume that's naturally diminished, or a slightly more defined pout, treatment is fully tailored and fully reversible.

Emily specialises in natural lip results — the kind where people notice you look good but can't quite put their finger on why. If you've been looking for a lip filler clinic on the Upper East Side that won't leave you looking overdone, book a consultation at 1025 Lexington Avenue.

Jawline and Chin Filler on the Upper East Side

Jawline and chin filler have become two of the most sought-after treatments for facial contouring in NYC. Used together, they can sharpen definition, improve facial symmetry, and create the kind of structured profile that photographs well and reads as healthy in person.

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At Sisu Clinic Upper East Side, chin and jawline filler treatments use hyaluronic acid to build structure and definition without surgery. Results are immediate, last 12–18 months on average, and can be adjusted over time as your aesthetic goals evolve.

This is a treatment that requires real injector skill — the chin and jawline are complex areas where placement matters enormously. Emily's background in aesthetic dermatology and advanced clinical training makes her well-placed to deliver results that are proportionate and natural-looking.

If you're considering chin filler or jawline contouring on the Upper East Side, Sisu Clinic on Lexington Avenue is worth your first appointment.

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TrapTox on the Upper East Side

TrapTox — Botox injected into the trapezius muscle — has gone from a niche treatment to one of the most talked-about aesthetics procedures in New York. It slims the shoulder and neck silhouette, relieves chronic tension in the upper back, and for many people produces a significant improvement in posture and day-to-day comfort.

Sisu Clinic Upper East Side offers TrapTox as a standalone treatment. The procedure takes around 20 minutes, requires no downtime, and results start to show at around 6–8 weeks, lasting up to 6 months. It's one of the most requested treatments at our Lexington Avenue clinic — particularly among patients who carry tension through the neck and shoulders from long hours at a desk.

For anyone working long hours at a desk, carrying tension through the shoulders, or simply looking to refine their neck and shoulder profile, TrapTox at our Upper East Side location is a straightforward starting point.

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Under-Eye Filler on the Upper East Side

Tear trough filler — used to address hollowness, dark circles, and the tired look that no amount of sleep seems to fix — is one of the most transformative treatments available at Sisu Clinic Upper East Side, and also one of the most technique-dependent.

The under-eye area is delicate. Placement matters more here than almost anywhere else on the face, and results that look natural require both the right product and a provider who understands the anatomy of the periorbital area. Emily's training and experience in aesthetic dermatology makes her well-suited to this treatment.

If you've been considering under-eye filler on the Upper East Side and want a clinic where the approach is conservative and the results are subtle, book a consultation at our Lexington Avenue clinic.

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Sculptra on the Upper East Side

For patients who want results that don't look like they came from a clinic, Sculptra® is often the answer. Unlike hyaluronic acid fillers which add immediate volume, Sculptra works by stimulating your body's own collagen production over time — creating a gradual improvement in skin quality, volume and structure that looks entirely natural.

At Sisu Clinic Upper East Side, Sculptra is available as a standalone treatment and as part of our combination packages. Results begin to show from around 4–5 weeks and can last up to two years, making it one of the most cost-effective options for long-term facial rejuvenation.

Emily has a particular interest in Sculptra for natural rejuvenation — it's one of the treatments she's most experienced with at the Upper East Side clinic.

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Rejuran on the Upper East Side

If you've been on aesthetics TikTok recently, you've probably come across Rejuran — the "salmon skin" treatment that's gone viral for its ability to deliver genuinely glowing, poreless skin. Sisu Clinic Upper East Side is one of the few clinics in NYC offering Rejuran microneedling.

The treatment uses polynucleotides derived from salmon DNA to repair, hydrate and regenerate the skin at a cellular level. The result is smoother texture, reduced pores, improved elasticity and the kind of skin quality that most people associate with expensive skincare routines — except it works from the inside out

If you're looking for Rejuran treatments on the Upper East Side or across New York City, Sisu Clinic on Lexington Avenue is now one of your closest options.

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Book at Sisu Clinic Upper East Side

Sisu Clinic is at 1025 Lexington Avenue, New York, NY 10021 — open Monday to Friday 10AM–8PM and Saturday 10AM–6PM.

You can book online at sisuclinic.com, call 561-948-6180, or email ues@sisuclinic.com.

Whether you're booking your first consultation or returning for a treatment you already know and trust, our Upper East Side team is ready.

Frequently Asked Questions

What Botox and filler treatments are available at Sisu Clinic Upper East Side?

Our Lexington Avenue clinic offers the full range of Sisu treatments, including Botox and Dysport for forehead lines, frown lines, and crow's feet; lip filler; jawline and chin filler; TrapTox; under-eye tear trough filler; Sculptra; and Rejuran microneedling. Every appointment begins with a free consultation so your provider can assess your goals and recommend the right approach for your face.

Who is the injector at Sisu Clinic Upper East Side?

Treatments at the Upper East Side location are delivered by Emily Canavarros, BSN, RN — a medically trained aesthetic injector with advanced clinical training and a particular focus on natural, balanced results. Emily has extensive experience across Sculptra, lip filler, and Rejuran microneedling.

How much does Botox cost at Sisu Clinic Upper East Side?

Botox and Dysport are priced at a flat $495 for three areas — forehead, frown lines, and crow's feet — with a fourth area free. There is no per-unit pricing, no upsells, and no hidden fees at checkout. A free consultation and complimentary 2-week dosage review are included with every appointment.

Where is Sisu Clinic Upper East Side located and what are the opening hours?

We're at 1025 Lexington Avenue, New York, NY 10021. The clinic is open Monday to Friday 10AM–8PM and Saturday 10AM–6PM. Appointments can be booked online at sisuclinic.com, by calling 561 948 6180, or by emailing ues@sisuclinic.com.

Is Sisu Clinic Upper East Side a doctor-led clinic?

Yes. Sisu Clinic is doctor-founded and doctor-led. Our clinical protocols are developed by our co-founders and applied consistently across all 27 locations worldwide. Every treatment at the Upper East Side clinic follows a medically supervised framework — prioritising safety, natural results, and a standard of care that goes beyond what you'd expect from a typical aesthetics clinic.

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