AI Makeover Promo

Botox That's You
Botox That's Natural

Premium, doctor-led
Botox at Sisu Clinic Mayfair.

Three areas plus a fourth area free,

for £225

Book Today

WE OFFER

Our AI Makeover

Our AI MakeoverPreview your Botox look for free.

Our AI Makeover
Transparent Pricing

Transparent PricingNo upsells, extra charges, or hidden fees.

Transparent Pricing
Free Consultation

Free Consultationand a complimentary 2-week Botox dosage review.

Free Consultation
Meet Our Medical-Led Teams

Meet Our Medical-Led TeamsOur providers are rigorously trained and consistently updated to ensure your experience is safe and results-driven.

Meet Our Medical-Led Teams

Get Get 3 areas of Botox
and enjoy a 4th area FREE -
choose from Lip Flip, ChinTox,
Gummy Smile, Bunny Lines, Brow Lift.

Book Today
Before and after anti-wrinkle treatment at Sisu Clinic
Natural botox results at Sisu Clinic
Dysport treatment results at Sisu Clinic
Sisu Clinic anti-wrinkle treatment
Dysport treatment results at Sisu Clinic
Sisu Clinic anti-wrinkle treatment

At Sisu Clinic Mayfair, every Botox treatment starts with a full-face consultation. Most patients walk in pointing at one line. We start by looking at the whole face — because the muscles work in pairs and groups, and softening one area without considering the others is how people end up with a heavy brow, a dropped expression, or that frozen look nobody asks for. Our doctors assess how you move, balance muscle strength across the face, and dose conservatively. The goal is always the same: results that look like rest, not work. Softer lines, lifted features, still completely you. Transparent flat-fee pricing — no surprises.

Botox in Mayfair — the Sisu Approach

At Sisu Clinic Mayfair, every Botox treatment starts with a full-face consultation. Most patients walk in pointing at one line. We start by looking at the whole face — because the muscles work in pairs and groups, and softening one area without considering the others is how people end up with a heavy brow, a dropped expression, or that frozen look nobody asks for. Our doctors assess how you move, balance muscle strength across the face, and dose conservatively. The goal is always the same: results that look like rest, not work. Softer lines, lifted features, still completely you. Transparent flat-fee pricing — no surprises.

Before Your Appointment. Your treatment begins with a medical consultation. We review your medical history, assess facial movement, and discuss your goals. If you're new to Botox, we'll explain everything in detail so you feel fully informed.

  • Avoid alcohol 24 hours before treatment
  • Avoid blood-thinning supplements if medically appropriate

During Treatment. The treatment itself takes approximately 10 to 15 minutes. Using ultra-fine needles, small amounts of Botox are injected into targeted muscles. Most patients describe the sensation as a small pinch. No anaesthesia is required — it's a lunchtime procedure. Many of our Mayfair patients return to work or to their day immediately after.

After Treatment. There is minimal downtime.

  • Avoid heavy exercise for 24 hours
  • Avoid lying flat for 4 hours
  • Avoid rubbing the treated area

You may experience minor redness or small bumps at injection sites, which typically resolve within 30 minutes.

What to Expect at Your Botox Appointment at Sisu Mayfair

Before Your Appointment. Your treatment begins with a medical consultation. We review your medical history, assess facial movement, and discuss your goals. If you're new to Botox, we'll explain everything in detail so you feel fully informed.

  • Avoid alcohol 24 hours before treatment
  • Avoid blood-thinning supplements if medically appropriate

During Treatment. The treatment itself takes approximately 10 to 15 minutes. Using ultra-fine needles, small amounts of Botox are injected into targeted muscles. Most patients describe the sensation as a small pinch. No anaesthesia is required — it's a lunchtime procedure. Many of our Mayfair patients return to work or to their day immediately after.

After Treatment. There is minimal downtime.

  • Avoid heavy exercise for 24 hours
  • Avoid lying flat for 4 hours
  • Avoid rubbing the treated area

You may experience minor redness or small bumps at injection sites, which typically resolve within 30 minutes.

Wrinkle Treatment

£225

Flat fee

Book Today
Checkmark

Three areas: forehead, glabella, crow's feet

Checkmark

Complimentary 2-week review and dose adjustment

Checkmark

Premium Botox at transparent pricing

Botox Timeline

Click a milestone to explore your journey

Day 1: Your treatment day

Welcome to the start of your Botox journey! Your practitioner administers precise, targeted injections. The treatment itself takes just 10–15 minutes. You may notice tiny bumps at the injection sites — completely normal and temporary.

Day 3: Subtle tightness kicks in

You'll start to notice a gentle tightness as the Botox begins working. Your skin feels firmer to the touch. This is the treatment settling in — a sign things are moving in the right direction!

Day 7: Smoothing out begins

By day 7, wrinkles and fine lines begin visibly smoothing out. This is often when patients first notice a real difference in the mirror. The full effect is still developing — the best is yet to come.

1–3 Months: Peak results & compliments!

You're glowing! This is the sweet spot — full results are in, skin looks refreshed and naturally smooth. Expect compliments from friends who can't quite put their finger on why you look so good.

3–4 Months: Time for your next appointment

As Botox naturally metabolises, movement gradually returns. This is the perfect time to book your next session to maintain your results. Regular treatments can also train muscles over time for longer-lasting effects.

💉
Day 1

Your treatment day

Welcome to the start of your Botox journey! Your practitioner administers precise, targeted injections. The treatment itself takes just 10–15 minutes. You may notice tiny bumps at the injection sites — completely normal and temporary.

MAYFAIR PATIENT TESTIMONIALS

Botox Reviews You Can Trust

Trustpilot
4.9
Google
4.8
Yelp
4.9
Mona Shayan
Mona ShayanVerified Patient

I had my anti wrinkle treatment with Dr Imana at Mayfair. She was so professional and lovely. I had many experiences for anti wrinkle treatment before in well known places in London, but I'm very happy with the outcome that I received after going to Sisu Clinic. I can say all was perfect and I highly recommend it 🤩🙏

Read more →
Gracie Convert
Gracie ConvertVerified Patient

First time trying Sisu I was with Dr.Nila, she was really nice it's only been two days and my results are already showing and looking great, would highly recommend her! Receptionists were so friendly also

Read more →
Kate O'Rourke
Kate O'RourkeVerified Patient

I always have a lovely experience at Sisu, they're very open and honest with me about treatments and what they think would or would not benefit. Dr Nila treated me today and she was extremely kind and made me feel comfortable! The treatment was relatively pain free and extremely efficient! Would definitely recommend.

Read more →
Misha V
Misha VVerified Patient

I had a great experience here, the clinic is very clean and nicely set out. The lady at reception was friendly and helpful. I had Botox with Dr Nila who was fantastic and really listened to my concerns first. I think it's the best Botox I've ever had. I'll definitely come back.

Read more →

Your Questions

Answered By Your Doctor

What is Botox and how does it work?

Botox is a prescription treatment made from botulinum toxin type A. It works by relaxing specific facial muscles so lines caused by repeated movement — like frown lines and crow's feet — appear softer. Results are temporary, which is why it is often used as part of a flexible, natural-looking treatment plan.

How long does Botox last?

Most Botox results last around 3 to 4 months, although this varies depending on the area treated, your muscle activity and how your body responds. In some cases, results can last a little longer with regular treatment, but the effects are not permanent. Your practitioner will assess your results at your complimentary 2-week review.

Does Botox hurt?

Botox is usually well tolerated. Most patients describe it as a small pinch rather than real pain, and the treatment itself is quick — often around 15 minutes. No general anaesthetic is needed, and most people return to normal activities straight after. Book your appointment at Sisu Mayfair today.

When will I see results from Botox?

You may start noticing a change within a few days, but full results usually develop after 7 to 14 days — that is when the treated muscles have fully relaxed and the smoother effect becomes most visible. Your complimentary 2-week review with your Mayfair practitioner is included with every appointment.

What areas can be treated with Botox?

At our Mayfair clinic, Botox can be used to treat:

The best areas for you depend on your facial anatomy and what result you want — assessed at your free consultation.

Is Botox safe?

When Botox is administered by a qualified medical professional, it is considered a well-established and widely used aesthetic treatment. At Sisu Mayfair, a proper consultation is always carried out first to check suitability, discuss medical history and plan treatment safely and conservatively. Meet our medical team.

Why choose Botox at Sisu Mayfair?

  • Doctor-led treatments — every injection by a medically qualified practitioner
  • Transparent flat-fee pricing — £225 for three areas with a fourth area free, no per-unit surprises
  • Free consultation — a clinical assessment, no commitment required
  • Natural-looking results — the goal is always refreshed, never overdone
  • Central Mayfair location at 55 Stratton Street, W1J 8LR
  • Thousands of treatments across UK and Ireland — see our patient reviews

Schedule your appointment at our Mayfair Clinic

Sisu Mayfair Location