Sisu Clinic Is Now Open at Arnotts Henry Street, Dublin

Sisu Clinic, Ireland’s leading doctor-led aesthetic clinic, is now open inside Arnotts, bringing our doctor-led approach to aesthetic medicine to the heart of Dublin city centre.

For eight years, we’ve been building Sisu Clinic in Ireland around a simple belief: aesthetic medicine should be personal, considered and guided by medical expertise. Opening at Arnotts marks an exciting new chapter for our team and an opportunity to welcome even more people into the Sisu experience.

Whether your interest lies in improving skin quality, exploring collagen-stimulating treatments or learning more about facial rejuvenation, we’re here to help you understand your options in a welcoming, patient-focused setting.

A New Destination for Aesthetic Treatments in Dublin City Centre

Henry Street is one of Dublin’s best-known shopping destinations, bringing together fashion, beauty and everyday city life. With our new location at Arnotts, we’re excited to make Sisu’s approach to aesthetic care accessible in this vibrant part of the city.

We know that choosing an aesthetic treatment is a personal decision. You may have a particular concern in mind, or you may simply want to understand how different treatments work and what could suit your skin.

Our approach starts with listening. Through a consultation, we can discuss your priorities, assess your suitability and explain the options available, helping you make an informed decision without pressure.

Explore Skin Rejuvenation and Injectable Treatments at Sisu Clinic at Arnotts Henry Street, Dublin

Our Arnotts Henry Street clinic offers the full range of Sisu's most sought-after treatments, delivered by our qualified medical team. Whether you are coming in for the first time or you are a long-standing Sisu patient looking for a more convenient location, everything you need is here.

Anti-Wrinkle Injections

Our most popular treatment, and for good reason. Anti-wrinkle injections at Sisu are precise, natural-looking, and tailored entirely to your face. We do not believe in frozen results. We believe in you, looking like the best version of yourself. Treatments typically take 15 to 20 minutes, making this the original lunch-break treatment.

Results last 3 to 4 months. Most patients return regularly and find their results improve over time.

Dermal Fillers

From subtle lip enhancement to jawline definition and cheek restoration, our doctors use premium fillers to add volume, restore contour, and create harmony across the face. Every filler treatment at Sisu begins with a thorough consultation. We will never recommend more than you need.

Sculptra

Sculptra is one of the most transformative treatments in modern aesthetics, and one of the most underappreciated. Unlike traditional fillers, Sculptra works by stimulating your own collagen production over time, delivering a gradual, natural-looking improvement in skin volume and structure that can last up to two years.

This is the treatment for patients who want results that look like they never had a treatment.

Polynucleotides

Polynucleotides are the skin treatment everyone is talking about in 2026, and Sisu has been at the forefront of this regenerative revolution. Derived from purified DNA fragments, polys work deep within the skin to stimulate cell renewal, improve hydration, reduce fine lines, and restore a luminous, healthy glow. The results are gradual, cumulative, and genuinely impressive.

Profhilo

If your skin has lost its bounce, its glow, or its firmness, Profhilo is one of the most effective treatments available. As one of the highest-concentration hyaluronic acid products on the market, Profhilo spreads through the skin to deeply hydrate and remodel tissue. Two sessions, spaced four weeks apart, are typically all it takes to see a remarkable difference.

Exosomes with Microneedling

Our advanced microneedling treatment is paired with exosome treatment for next-generation skin renewal. Microneedling creates controlled micro-channels in the skin, and exosomes, which are powerful cell-signalling molecules, are delivered directly into those channels to accelerate healing, stimulate collagen, and dramatically improve skin texture, tone, and radiance.

This combination is particularly effective for patients dealing with skin laxity, uneven texture, dullness, or the early signs of ageing.

The Sisu Packages

Not sure where to start? Our curated treatment packages take the guesswork out of your aesthetic journey. The Sisu Signature Package combines our most complementary treatments into one personalised plan, designed by our doctors to give you the most impactful results for your specific goals and budget.

• Anti-Wrinkle Injections: smooths lines and relaxes muscles. Ideal for foreheads, crow's feet and frown lines.
• Dermal Fillers: restores volume and contour. Ideal for lips, cheeks, jawline and temples.
• Sculptra: stimulates collagen over time. Ideal for full-face rejuvenation and volume loss.
• Polynucleotides: regenerates skin at a cellular level. Ideal for skin quality, hydration and fine lines.
• Profhilo: deep hydration and tissue remodelling. Ideal for dull, dehydrated, lax skin.
• Microneedling + Exosomes: advanced skin renewal. Ideal for texture, tone, radiance and early ageing.

What Makes Sisu Different: Doctor-Led, Always

At Sisu, every treatment is delivered by a qualified medical professional. We were founded in 2018 by doctors James Cotter and Brian Cotter alongside entrepreneur Pat Phelan, with a singular mission: to make safe, effective aesthetic medicine accessible to everyone. That founding principle has never changed. Doctor-led care is not a marketing phrase for us. It is the foundation everything else is built on.

What that means for you, in practice:

• Your consultation is with a medical professional, not a sales advisor. You will receive an honest assessment of what will and will not work for your face and your goals.
• Your treatment is performed by a qualified practitioner with deep clinical knowledge of facial anatomy, product behaviour, and safety protocols.
• Your aftercare is supported by a team that is available to you if you have questions or concerns after your appointment.
• You will never be oversold. If a treatment is not right for you, we will tell you. That commitment is what has earned Sisu a five-star reputation across tens of thousands of patient reviews.

Your First Visit: What to Expect

Walking into a medical aesthetic clinic for the first time can feel like a big step. We have designed every part of the Sisu experience to make sure it does not feel that way.

Here is what happens when you come to see us at Arnotts Henry Street:

1. Consultation first, always. Every new patient begins with a free consultation. This is your opportunity to talk through your concerns, your goals, and any questions you have, without any obligation to book a treatment.
2. A personalised treatment recommendation. Your practitioner will assess your face, listen to what you want to achieve, and recommend only what is genuinely right for you.
3. Treatment, when you are ready. Many treatments can be carried out on the same day as your consultation. Anti-wrinkle injections and skin treatments like Profhilo are quick, comfortable, and require no significant downtime.
4. Aftercare support. You will leave with clear aftercare guidance and access to our team if you have any questions in the days that follow.

First time? Use our Sisu Vision AI tool to simulate how treatments could look on your own face before you even book. It takes a selfie, generates a realistic before-and-after preview, and helps you walk into your consultation already knowing what you want.

Find Us at Arnotts Henry Street

Sisu Clinic at Arnotts Henry Street is now open. Come and find us inside the store, and let us show you what doctor-led aesthetics really feels like.

Opening Hours:

• Thursday: 10:00 AM – 8:00 PM
• Friday: 10:00 AM – 7:00 PM
• Saturday: 9:00 AM – 7:00 PM

Location: Arnotts, Henry Street, Dublin 1

Same-week appointments are available. No waiting lists. No long lead times. Book online now and take the first step toward results you will genuinely love.

This new location is an exciting part of our story, but the values behind it remain unchanged: medical expertise, personalised care and a considered approach to aesthetic treatments.

Sisu Clinic is now open at Arnotts Henry Street. We can’t wait to welcome you and help you explore the options that feel right for you.

Discover our treatments and book a consultation.